Research Competition Tackles Rare CFTR Mutations

It is with great enthusiasm that Génome Québec and Cystic Fibrosis Canada announce the launch of the Tackle Rare, Orphan CFTR Mutations Competition to support research on rare mutations for which no treatment is available, with the long-term goal of developing novel therapies. The two organizations aim to jointly invest $1.2M to support projects with a total budget of $300,000 - $600,000 per project for a period of three years. 

This competition targets research project proposals that have the potential to improve, in an inclusive manner, the well-being of all people affected by cystic fibrosis, and overall contribute to the democratization of research while increasing public awareness.  

Applications will need to support the following objectives:

• Specifically address forms of cystic fibrosis caused by rare mutations that are not responsive to the treatments currently available and support the priorities of the cystic fibrosis community. Targeted mutations are class I mutations (nonsense, frameshift, splicing) that do not produce functional CFTR protein. 
• Improve the understanding of the mechanism of these mutations and/or lay the basis for the development of novel therapies, using omics approaches.

In addition, the competition aims to mobilize the Québec research community, while ensuring the needs of the cystic fibrosis community are considered. This competition is open only to researchers affiliated with an eligible institution in the province of Québec.  

Important information 

Registration is mandatory and the deadline to submit your application is August 27, 2024, at noon (EDT).  For more information, documents, and dates for this funding opportunity, please click here. 

For all questions, please contact Annina Spilker, Manager of programs and strategic initiatives, at: [email protected]. 

We invite you to share this notice with people that could be interested in this competition.